Wednesday, January 23, 2008

Stop smoking and lose weight?

OBESITY TREATMENT

Under development by Sanofi-Synthelabo, rimonabant (Acomplia) shows promise as both a weight-loss and smoking-cessation drug. Research indicates that rimonabant significantly reduces abdominal obesity, raises high-density lipoprotein ("good" cholesterol) levels, lowers triglyceride levels, and improves other markers of metabolic syndrome.

In one study, obese patients taking rimonabant lost an average of 20 pounds (9 kg) in a year. In a second study, the drug helped smokers nearly double their chances of kicking the habit in 10 weeks-and, as a bonus, overweight subjects also dropped about a pound each. The most common adverse reactions were nausea, dizziness, and upper respiratory tract infections.

Rimonabant is the first of a new class of drugs that block certain receptors on brain and fat cells belonging to the endocannabinoid (EC) system. Nicotine and the active ingredient in marijuana both attach to EC system receptors. Blocking these receptors seems to reduce both appetite and the urge to smoke.

2 comments:

Helga said...

This ones very informative..
Does smoking can also cause diabetes.?



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